If depressed, your chances of survival are best without pharma.
Of course, depression as such increases your chances of death but most commonly used drugs do too and none of them reduces the mortality rate.
Oswaldo P. Almeida et al. Depression, Antidepressant Use and Mortality in Later Life: The Health in Men Study. PLoS ONE 2010. Open access.
Fig. 3. The mortality hazard ratio associated with the use tricyclic antidepressants (▴), selective serotonin inhibitors (SSRIs)(▪), other antidepressants (x) and all antidepressants combined (⧫) is shown in the figure.
Of course, this says nothing about their effectivity in making you happy but the same can be said of heroine, right?